"Yet the doctrine that ''man is a machine'' was argued most forcefully in 1751, long before the theory of evolution became generally accepted, by de La Mettrie; and the theory of evolution gave the problem an even sharper edge, by suggesting there may be no clear distinction between living matter and dead matter. And, in spite of the victory of the new quantum theory, and the conversion of so many physicists to indeterminism de La Mettrie's doctrine that man is a machine has perhaps more defenders than before among physicists, biologists and philosophers; especially in the form of the thesis that man is a computer."〔Popper, K.: ''Of Clouds and Clocks'', included in ''Objective Knowledge'', revised, 1978, p. 224.〕